An epidemiologist found five cases of “big toe cancer” in the Yukon Territory. Because there
were only a few cases, the epidemiologist decided to conduct a matched case-control study to
determine whether shoe size larger than 9 is a risk factor for big toe cancer. Cases were
individually matched to one control for daily activity, history of athlete’s foot, and history of
ingrown toenails. The following data were gathered:
Shoe size > 9
Pair Case Control
1 Yes No
2
No
No
3
No Yes
4 Yes Yes
5
No Yes
1. Compute the proper measure of association.
2. Interpret your results.
3. If you were to investigate a rare cancer in Lynchburg, where might you look for data?
What would be necessary legally and ethically to be able to utilize this data set(s)?
